Matrine‐Type Alkaloids from the Seeds of Sophora alopecuroides and Their Potential Anti‐inflammatory Activities
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چکیده
منابع مشابه
Isolation and characterization of a novel lectin with antifungal and antiproliferative activities from Sophora alopecuroides seeds.
Sophora alopecuroides lectin (SAL), a novel lectin from the seeds of Sophora alopecuroides, was purified by ion-exchange chromatography on diethylaminoethyl (DEAE)- and carboxymethyl (CM)-Sepharose columns, followed by gel filtration on a Sephadex 75 10/300 GL column. SAL was found to be a monomer of 39916.3 Da, as determined by tricine-sodium dodecyl sulphate-polyacrylamide gel electrophoresis...
متن کاملExtraction and isolation of alkaloids of Sophora alopecuroides and their anti-tumor effects in H22 tumor-bearing mice.
BACKGROUND Alkaloids of Sophora alopecuroides have good biological activity, and are widely used in clinical settings, which not only have pharmacological activities of anti-cancer, cancer suppression, as well as the inhibition, and killing of various microorganisms; but also possess extensive pharmacological effects on immune system, nervous system and cardiovascular system. The objective of t...
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Staphylococcus epidermidis (S. epidermidis) is an opportunistic pathogen with low pathogenicity and a cause of the repeated outbreak of bovine mastitis in veterinary clinical settings. In this report, a biofilm model of S. epidermidis was generated and the minimal inhibitory concentration (MIC) and sub-MIC (SMIC) on bacterial cultures were assessed for the following agents: total alkaloids of S...
متن کاملCharacterisation and antimicrobial activity of Sophora alopecuroides L. var. alopecuroides alkaloid extracts
Th e aerial parts and seeds of Sophora alopecuroides L. var. alopecuroides growing in Turkey were investigated for their alkaloid compositions and antimicrobial activities. Th e alkaloid extracts were analysed by capillary gas chromatography-mass spectrometry (GC-MS). Th e main components were identifi ed as sophoridine (33.07%), matrine (24.03%), and sophocarpine (8.01%) in the aerial parts, a...
متن کاملMorphine withdrawal attenuating effect, toxicity and alkaloid composition of Sophora alopecuroides L. var. alopecuroides
Background and objectives: The seedsof Sophora alopecuroides L. var. alopecuroides may benefit treatment of opioid dependence. Therefore, the plant alkaloid composition, toxicity and effects on morphine withdrawal were studied. Methods: The alkaloid composition was determined by GC and GC/MS analysis. Mice were made dependent by morphine injec...
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ژورنال
عنوان ژورنال: Chemistry & Biodiversity
سال: 2021
ISSN: 1612-1872,1612-1880
DOI: 10.1002/cbdv.202001066